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Malaysia Airlines said a flight carrying 239 people from Kuala Lumpur to Beijing went missing early Saturday, and the airline was notifying next of kin in a sign it feared the worst. The airline said flight MH370 disappeared at 2:40 am local time (1840 GMT Friday), about two hours after leaving Kuala Lumpur International Airport. It had been due to arrive in Beijing at 6:30 am local time (2230 GMT Friday). The Boeing 777-200 was carrying 227 passengers, including two infants, from 13 different nationalities, and 12 crew members.
A potent new painkiller hit the US market this week, despite warnings from top experts that the drug may deliver a deadly setback in America's battle with opioid addiction. Zohydro ER can contain 10 times the amount of hydrocodone as the most popular prescription painkiller, Vicodin, and is easily crushable so it could be snorted, bearing none of the recent safeguards added to pills like OxyContin (oxycodone). In a nation where some 15,000 people die annually from prescription painkiller use, the drug's approval has raised alarm among doctors, lawmakers and relatives of those lost to overdose. Two senators have launched an investigation into practices by the US Food and Drug Administration, amid allegations that pharmaceutical companies eager for a chunk of the $9 billion painkiller market may have paid to influence regulators' decisions.