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By Nidal al-Mughrabi GAZA/JERUSALEM (Reuters) - A three-day ceasefire between Israel and Palestinian militant groups in the Gaza Strip went into effect on Friday, with negotiators due to travel to Cairo to discuss a longer-term solution. The 72-hour break announced in a joint statement by U.S. Secretary of State John Kerry and U.N. Secretary-General Ban Ki-moon was the most ambitious attempt so far to end more than three weeks of fighting, and followed mounting international alarm over a rising Palestinian civilian death toll. After the ceasefire began at 1 a.m. EDT (0500 GMT), Gaza's streets began to fill with Palestinian families. In Israel, sirens that have sent tens of thousands running for shelter daily fell silent.